Charlotte is the most populous city in the U.S. state of North Carolina. Located in the Piedmont, it is the county seat of Mecklenburg County. In 2019, the U.S. Census Bureau estimated the population was 885,708, making it the 15th-most populous city in the U.S. and the second-largest in the Southeast behind Jacksonville, Florida. The city is the cultural, economic, and transportation center of the Charlotte metropolitan area, whose population ranks 22nd in the U.S., and had a population of 2,569,213, in 2018. The Charlotte metropolitan area is part of a sixteen-county market region or combined statistical area with a 2018 census-estimated population of 2,728,933.